When high-energy electrons from a scanning transmission electron microscope (STEM) are incident on a liquid, the overwhelming majority of the chemical reactions which might be noticed are induced by the radiolysis breakdown of the liquid molecules. In the research of liquids, the radiolysis merchandise of pure water are well-known, and their price of formation for a given flux of high-energy electrons has been studied intensively over the previous couple of years for uniform TEM illumination.
In this paper, we reveal that the temporal and spatial distribution of the electron illumination can considerably have an effect on the remaining density of radiolysis merchandise in water and even change the sort of response going down. We simulate the advanced array of doable spatial/temporal distributions of electrons which might be accessible experimentally by controlling the dimension, the scan price and the hopping distance of the electron probe in STEM mode after which examine the outcomes to the uniformly illuminated TEM mode of imaging.
By distributing the electron dose each spatially and temporally in the STEM by a randomised “spot-scan” mode of imaging, the diffusion overlap of the radiolysis merchandise could be diminished, and the ensuing reactions could be extra readily managed. This management permits the decision of the photographs to be separated from the pace of the induced response (which relies on beam present alone) and this side of the experiment will permit a variety of chemical reactions to be uniquely tailor-made and noticed in all liquid cell STEM experiments.
Progress in the Theory of X-ray Spectroscopy: From Quantum Chemistry to Machine Learning and Ultrafast Dynamics
The improvement of high-brilliance third- and fourth-generation mild sources equivalent to synchrotrons and X-ray free-electron lasers (XFELs), the emergence of laboratory-based X-ray spectrometers, and instrumental and methodological advances in X-ray absorption (XAS) and (non)resonant emission (XES and RXES/RIXS) spectroscopies have had far-reaching results throughout the pure sciences.
However, new sorts of experiments, and their ever-higher decision and knowledge acquisition charges, have introduced acutely into focus the problem of precisely, shortly, and cost-effectively analyzing the knowledge; a far-from-trivial job that calls for detailed theoretical calculations which might be able to capturing satisfactorily the underlying physics.
The previous decade has seen important advances in the concept of core-hole spectroscopies for this goal, pushed by all of the developments above and-crucially-a surge in demand. In this Perspective, we focus on the challenges of calculating core-excited states and spectra, and state-of-the-art developments in digital construction concept, dynamics, and data-driven/machine-led approaches towards their higher description.
Chemistry Informer Libraries: Conception, Early Experience, and Role in the Future of Cheminformatics
ConspectusThe artificial chemistry literature historically stories the scope of recent strategies utilizing easy, nonstandardized check molecules which have unsure relevance in utilized synthesis. In addition, revealed examples closely favor optimistic response outcomes, and failure is never documented. In this atmosphere, artificial practitioners have insufficient info to know whether or not any given methodology is appropriate for the job at hand.
Moreover, the incomplete nature of revealed knowledge makes it poorly suited to the creation of predictive reactivity fashions through machine studying approaches. In 2016, we reported the idea of chemistry informer libraries as standardized units of medium- to high-complexity substrates with relevance to pharmaceutical synthesis as demonstrated utilizing a multidimensional precept part evaluation (PCA) comparability to the physicochemical properties of marketed medicine.
We confirmed how informer libraries may very well be used to guage main artificial strategies with the full seize of success and failure and the way this information might result in improved response circumstances with a broader scope with respect to related purposes. In this Account, we describe the progress made and classes realized in subsequent research utilizing informer libraries to profile eight extra response lessons. Examining broad tendencies throughout a number of varieties of bond disconnections towards a standardized chemistry “measuring stick” has enabled comparisons of the relative potential of various strategies for purposes in advanced synthesis and has recognized alternatives for additional improvement.
Furthermore, the highly effective mixture of informer libraries and 1536-well-plate nanoscale response screening has allowed the parallel analysis of scores of artificial strategies in the similar experiment and as such illuminated an essential function for informers as half of a bigger knowledge technology workflow for predictive reactivity modeling. Using informer libraries as problem-dense, sturdy filters has allowed broad units of response circumstances to be narrowed down to people who show the highest tolerance to advanced substrates.
These greatest circumstances can then be used to survey broad swaths of substrate house utilizing nanoscale chemistry approaches. Our experiences and people of our collaborators from a number of tutorial laboratories making use of informer libraries in these contexts have helped us determine a number of areas for potential enhancements to the strategy that may improve their ease of use, utility in producing interpretable outcomes, and ensuing uptake by the broader group. As we proceed to evolve the informer library idea, we consider it should play an ever-increasing function in the way forward for the democratization of high-throughput experimentation and knowledge science-driven artificial methodology improvement.
A co-opted steroid synthesis gene, maintained in sorghum however not maize, is related to a divergence in leaf wax chemistry
Virtually all land vegetation are coated in a cuticle, a waxy polyester that forestalls nonstomatal water loss and is essential for warmth and drought tolerance. Here, we describe a possible genetic foundation for a divergence in cuticular wax chemistry between Sorghum bicolor, a drought tolerant crop extensively cultivated in sizzling climates, and its shut relative Zea mays (maize).
Combining chemical analyses, heterologous expression, and comparative genomics, we reveal that: 1) sorghum and maize leaf waxes are related at the juvenile stage however, after the juvenile-to-adult transition, sorghum leaf waxes are wealthy in triterpenoids which might be absent from maize; 2) biosynthesis of the majority of sorghum leaf triterpenoids is mediated by a gene that maize and sorghum each inherited from a typical ancestor however that’s solely functionally maintained in sorghum; and three) sorghum leaf triterpenoids accumulate in a spatial sample that was beforehand proven to strengthen the cuticle and reduce water loss at excessive temperatures.
 Neuroserpin Antibody |
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| AF4065 | Affbiotech | 200ul | EUR 376 |
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Description: The antibody detects endogenous level of total Neuroserpin protein. |
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Neuroserpin Antibody |
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| ABF4065 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) Neuroserpin (SERPINI1) Antibody |
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| abx025697-400ul | Abbexa | 400 ul | EUR 523 |
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Neuroserpin (SERPINI1) Antibody |
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| abx025697-80l | Abbexa | 80 µl | EUR 286 |
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Neuroserpin (SERPINI1) Antibody |
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| 20-abx115478 | Abbexa |
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Neuroserpin (SERPINI1) Antibody |
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| 20-abx123763 | Abbexa |
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 Antibody) Neuroserpin (NSP) Antibody |
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| 20-abx128085 | Abbexa |
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Neuroserpin (NSP) Antibody |
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| 20-abx173802 | Abbexa |
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 Neuroserpin Conjugated Antibody |
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| C21618 | SAB | 100ul | EUR 397 |
Neuroserpin (SERPINI1) Antibody |
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| abx235681-100ug | Abbexa | 100 ug | EUR 509 |
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Neuroserpin (SERPINI1) Antibody |
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| abx332186-100ul | Abbexa | 100 ul | EUR 425 |
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Neuroserpin (SERPINI1) Antibody |
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| abx433030-200ul | Abbexa | 200 ul | EUR 384 |
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Neuroserpin (SERPINI1) Antibody |
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| 20-abx301904 | Abbexa |
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 anti- Neuroserpin antibody |
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| FNab05681 | FN Test | 100µg | EUR 548.75 |
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Description: Antibody raised against Neuroserpin |
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 Anti-Neuroserpin antibody |
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| PAab05681 | Lifescience Market | 100 ug | EUR 386 |
Anti-Neuroserpin antibody |
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| STJ70678 | St John's Laboratory | 100 µg | EUR 359 |
 Neuroserpin protein |
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| 30R-AN043 | Fitzgerald | 25 ug | EUR 273 |
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Description: Purified recombinant Human Neuroserpin protein |
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 Neuroserpin, human |
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| RC513-13 | Bio Basic | 5ug | EUR 101.33 |
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 Antibody (HRP)) Neuroserpin (SERPINI1) Antibody (HRP) |
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| 20-abx317628 | Abbexa |
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 Antibody (FITC)) Neuroserpin (SERPINI1) Antibody (FITC) |
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| 20-abx317629 | Abbexa |
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 Antibody (Biotin)) Neuroserpin (SERPINI1) Antibody (Biotin) |
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| 20-abx317630 | Abbexa |
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 Anti-Neuroserpin/SERPINI1 Antibody |
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| PB9744 | BosterBio | 100ug/vial | EUR 294 |
 Neuroserpin, human recombinant |
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| 7181-10 | Biovision | EUR 229 | |
Neuroserpin, human recombinant |
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| 7181-50 | Biovision | EUR 675 | |
 Neuroserpin Blocking Peptide |
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| AF4065-BP | Affbiotech | 1mg | EUR 195 |
) Recombinant Neuroserpin (NSP) |
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| 4-RPD380Hu01 | Cloud-Clone |
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Description: Recombinant Human Neuroserpin expressed in: E.coli |
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) Anti-Neuroserpin (1D10) |
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| YF-MA10693 | Abfrontier | 100 ug | EUR 363 |
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Description: Mouse monoclonal to Neuroserpin |
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) Anti-Neuroserpin (1E10) |
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| YF-MA14705 | Abfrontier | 100 ug | EUR 363 |
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Description: Mouse monoclonal to Neuroserpin |
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 Polyclonal Goat Anti-Neuroserpin Antibody |
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| APR12136G | Leading Biology | 0.1 mg | EUR 484 |
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Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-Neuroserpin . This antibody is tested and proven to work in the following applications: |
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 Polyclonal Antibody (Human)) Neuroserpin (NSP) Polyclonal Antibody (Human) |
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| 4-PAD380Hu01 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP) |
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 Protein) Human Neuroserpin (NSP) Protein |
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| 20-abx166478 | Abbexa |
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 Neuroserpin ELISA KIT|Human |
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| EF001194 | Lifescience Market | 96 Tests | EUR 689 |
, Human) Neuroserpin (CHO-expressed), Human |
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| HY-P7270 | MedChemExpress | 50ug | EUR 360 |
 Recombinant Human Neuroserpin Protein |
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| PROTQ99574-2 | BosterBio | 25ug | EUR 317 |
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Description: Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB). Recombinant human neuroserpin is a 44.8 kDa non-glycosylated protein containing 395 amino-acid residues. |
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 Human Neuroserpin ELISA Kit |
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| RK00131 | Abclonal | 96 Tests | EUR 521 |
 Polyclonal Antibody (Human), APC) Neuroserpin (NSP) Polyclonal Antibody (Human), APC |
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| 4-PAD380Hu01-APC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with APC. |
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 Polyclonal Antibody (Human), Biotinylated) Neuroserpin (NSP) Polyclonal Antibody (Human), Biotinylated |
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| 4-PAD380Hu01-Biotin | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with Biotin. |
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 Polyclonal Antibody (Human), Cy3) Neuroserpin (NSP) Polyclonal Antibody (Human), Cy3 |
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| 4-PAD380Hu01-Cy3 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with Cy3. |
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 Polyclonal Antibody (Human), FITC) Neuroserpin (NSP) Polyclonal Antibody (Human), FITC |
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| 4-PAD380Hu01-FITC | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with FITC. |
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 Polyclonal Antibody (Human), HRP) Neuroserpin (NSP) Polyclonal Antibody (Human), HRP |
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| 4-PAD380Hu01-HRP | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with HRP. |
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 Polyclonal Antibody (Human), PE) Neuroserpin (NSP) Polyclonal Antibody (Human), PE |
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| 4-PAD380Hu01-PE | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with PE. |
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, Clone: 1D10) Monoclonal Neuroserpin Antibody (clone 1D10), Clone: 1D10 |
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| AMM06649G | Leading Biology | 0.05mg | EUR 528 |
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Description: A Monoclonal antibody against Human Neuroserpin (clone 1D10). The antibodies are raised in Mouse and are from clone 1D10. This antibody is applicable in WB and IHC-P, E |
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 Polyclonal Antibody (Human), APC-Cy7) Neuroserpin (NSP) Polyclonal Antibody (Human), APC-Cy7 |
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| 4-PAD380Hu01-APC-Cy7 | Cloud-Clone |
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Description: A Rabbit polyclonal antibody against Human Neuroserpin (NSP). This antibody is labeled with APC-Cy7. |
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 ELISA Kit) Human Neuroserpin (NSP) ELISA Kit |
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| DLR-NSP-Hu-48T | DL Develop | 48T | EUR 517 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Neuroserpin (NSP) in samples from serum, plasma or other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| DLR-NSP-Hu-96T | DL Develop | 96T | EUR 673 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Neuroserpin (NSP) in samples from serum, plasma or other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| 20-abx152509 | Abbexa |
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 Mouse Neuroserpin, Serpini1 ELISA KIT |
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| ELI-45671m | Lifescience Market | 96 Tests | EUR 865 |
 Protein (Active)) Human Neuroserpin (NSP) Protein (Active) |
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| 20-abx655786 | Abbexa |
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 CLIA Kit) Human Neuroserpin (NSP) CLIA Kit |
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| 20-abx494241 | Abbexa |
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 Chicken Neuroserpin, SERPINI1 ELISA KIT |
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| ELI-38297c | Lifescience Market | 96 Tests | EUR 928 |
 Human Neuroserpin, SERPINI1 ELISA KIT |
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| ELI-36796h | Lifescience Market | 96 Tests | EUR 824 |
ELISA Kit) Human Neuroserpin(NSP)ELISA Kit |
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| QY-E01619 | Qayee Biotechnology | 96T | EUR 361 |
Human Neuroserpin (NSP) ELISA Kit |
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| SED380Hu-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 4731.5 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Neuroserpin (NSP) in serum, plasma and other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| SED380Hu-1x48wellstestplate | Cloud-Clone | 1x48-wells test plate | EUR 477.3 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Neuroserpin (NSP) in serum, plasma and other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| SED380Hu-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 639 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Neuroserpin (NSP) in serum, plasma and other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| SED380Hu-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 2575.5 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Neuroserpin (NSP) in serum, plasma and other biological fluids. |
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Human Neuroserpin (NSP) ELISA Kit |
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| 4-SED380Hu | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Neuroserpin (NSP) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Human Neuroserpin (NSP) ELISA Kit |
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| RDR-NSP-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 544 |
Human Neuroserpin (NSP) ELISA Kit |
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| RDR-NSP-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 756 |
Human Neuroserpin (NSP) ELISA Kit |
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| RD-NSP-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 521 |
Human Neuroserpin (NSP) ELISA Kit |
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| RD-NSP-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 723 |
) ELISA kit for Human NSP (Neuroserpin) |
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| ELK3790 | ELK Biotech | 1 plate of 96 wells | EUR 432 |
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Description: A sandwich ELISA kit for detection of Neuroserpin from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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) ELISA kit for Human Neuroserpin (SERPINI1) |
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| KTE60688-48T | Abbkine | 48T | EUR 332 |
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Description: Quantitative sandwich ELISA for measuring Human Neuroserpin (SERPINI1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Neuroserpin (SERPINI1) |
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| KTE60688-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2115 |
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Description: Quantitative sandwich ELISA for measuring Human Neuroserpin (SERPINI1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Human Neuroserpin (SERPINI1) |
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| KTE60688-96T | Abbkine | 96T | EUR 539 |
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Description: Quantitative sandwich ELISA for measuring Human Neuroserpin (SERPINI1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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 Recombinant Human SerpinI1/ Neuroserpin Protein, Untagged, E.coli-100ug |
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| QP10160-ec-100ug | EnQuireBio | 100ug | EUR 988 |
 Recombinant Human SerpinI1/ Neuroserpin Protein, Untagged, E.coli-250ug |
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| QP10160-ec-250ug | EnQuireBio | 250ug | EUR 1731 |
 Recombinant Human SerpinI1/ Neuroserpin Protein, Untagged, E.coli-25ug |
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| QP10160-ec-25ug | EnQuireBio | 25ug | EUR 290 |
 Recombinant Human SerpinI1/ Neuroserpin Protein, Untagged, E.coli-5ug |
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| QP10160-ec-5ug | EnQuireBio | 5ug | EUR 154 |
 H2B Antibody Antibody |
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| AF4659 | Affbiotech | 200ul | EUR 376 |
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Description: H2B Antibody Antibody detects endogenous levels of H2B. |
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 CD11b Antibody Antibody |
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| ABD2911 | Lifescience Market | 100 ug | EUR 438 |
 anti- Antibody^Polyclonal antibody control antibody |
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| LSMab09882 | Lifescience Market | 100 ug | EUR 438 |
 Antibody) Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx008109 | Abbexa |
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 Antibody) Anti-Glycolipid Antibody (AGA) Antibody |
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| 20-abx004855 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx123734 | Abbexa |
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Anti-Glycolipid Antibody (AGA) Antibody |
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| abx036399-100ug | Abbexa | 100 ug | EUR 391 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx014333 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx033330-400ul | Abbexa | 400 ul | EUR 523 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx033330-80l | Abbexa | 80 µl | EUR 286 |
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 Antibody) Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319900 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319901 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319905 | Abbexa |
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Anti-Glycoprotein Antibody (GP) Antibody |
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| 20-abx319913 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| abx234901-100ug | Abbexa | 100 ug | EUR 551 |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx324434 | Abbexa |
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Ly1 Antibody Reactive (LYAR) Antibody |
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| 20-abx311665 | Abbexa |
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Anti-Glycolipid Antibody (AGA) Antibody |
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| abx230204-100ug | Abbexa | 100 ug | EUR 481 |
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 Anti-Anti-SEPT6 antibody antibody |
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| STJ11100949 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. |
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 Anti-Anti-SEPT9 Antibody antibody |
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| STJ111369 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
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 Anti-Anti-SEPT11 Antibody antibody |
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| STJ111530 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT4 Antibody antibody |
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| STJ112276 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. |
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 Anti-Anti-SEPT2 Antibody antibody |
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| STJ25475 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT5 Antibody antibody |
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| STJ25477 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. |
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 Anti-Anti-SEPT8 Antibody antibody |
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| STJ25479 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Anti-Anti-SEPT2 Antibody antibody |
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| STJ28365 | St John's Laboratory | 100 µl | EUR 277 |
 Anti-Anti-SEPT7 Antibody antibody |
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| STJ28963 | St John's Laboratory | 100 µl | EUR 277 |
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Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. |
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These findings uncover the chance for resurrection of a cuticular triterpenoid-synthesizing gene in maize that would create a extra heat-tolerant water barrier on the plant’s leaf surfaces. They additionally present a elementary understanding of sorghum leaf waxes that can inform efforts to divert floor carbon to intracellular storage for bioenergy and bioproduct improvements.