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ISN International Society for Neurochemistry

The International Society for Neurochemistry (ISN) organizes its 7th ISN Special Neurochemistry Conference on SYNAPTIC FUNCTION AND DYSFUNCTION IN BRAIN DISEASES. It is with great pleasure that we invite you to Coimbra, Portugal, next June to attend this conference.

Understanding how synapses are assembled, how their function is regulated and how it is modified by neuronal activity is essential to understand the brain. Dysregulation of synaptic function is thought to underlie schizophrenia, autism, depression and addiction, but also to be an early event in neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease, and in brain injury and stroke. Recent methodological advances have paved the way to a better understanding of synaptopathies, and of the consequent dysregulation of neural circuitry that contributes to these diseases.

An outstanding group of speakers from around the globe will share their expertise in an informal setting. The conference will be a dynamic forum for scientific exchange and a unique opportunity to discuss recent findings on the mechanisms that govern synapse formation, neurotransmitter release, post-synaptic receptor trafficking, synaptic plasticity, neuronal circuits and cognition and behavior. These topics will also be considered in the scope of their relevance for mechanisms of neurodevelopmental and neurodegenerative disorders.

We look forward to welcoming you in Coimbra!

The Organising Committee









Conference Topics

• Synapse formation and neurotransmitter receptors
• Synaptic architecture
• Intracellular trafficking and protein dynamics
• Pre- and post-synaptic function
• Synaptic plasticity and memory
• Neuronal circuits in the healthy and diseased brain
• Molecular mechanisms of neuropsychiatric disorders

Keynote Speakers

Rui Costa
 (Champalimaud Foundation, Lisbon, Portugal)
Daniel Choquet
(Interdisciplinary Institute for NeuroScience, Université Bordeaux, France)
Guoping Feng
 (McGovern Institute, MIT, Cambridge, MA)
Casper Hoogenraad
 (Utrecht University, The Netherlands)
Richard L. Huganir
 (Johns Hopkins University, Baltimore, MD)
Alcino Silva
 (UCLA, Los Angeles, CA)
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